MRI based quantification of outflow boundary conditions for wall shear stress calculations in stenosed human carotid bifurcations
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منابع مشابه
The impact of scaled boundary conditions on wall shear stress computations in atherosclerotic human coronary bifurcations.
The aim of this study was to determine if reliable patient-specific wall shear stress (WSS) can be computed when diameter-based scaling laws are used to impose the boundary conditions for computational fluid dynamics. This study focused on mildly diseased human coronary bifurcations since they are predilection sites for atherosclerosis. Eight patients scheduled for percutaneous coronary interve...
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Carotid arteries are a common site of atherosclerotic lesion development. Computational fluid dynamics models suggest that flow disturbances associated with stenosis can contribute to the initiation and progression of vascular wall pathologies. The main goal of this study is to present an investigation on the overall influence of assumptions regarding the outflow boundary conditions in hemodyna...
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The purpose of this paper is to complement the characterization of patient-specific carotid artery bifurcation hemodynamics based on image data obtained by Doppler ultrasound imaging. A methodology for patient-specific 3D luminal surface reconstruction followed by structured hexahedral meshing of the volume and blood flow simulation is presented. Quantitative descriptors of the flow based on wa...
متن کامل4D MRI-based wall shear stress quantification in the carotid bifurcation: a validation study in volunteers using computational fluid dynamics
Background Remodeling of the vessel wall is associated with wall shear stress (WSS) magnitude (Malek, 1999). It has been suggested that local low or high WSS may respectively promote or prevent atherosclerotic lesions in the carotid vessel wall. The current procedure for WSS quantification is computational fluid dynamics (CFD), which is time-consuming and not always patient-specific. In the pas...
متن کاملHemodynamics of human carotid artery bifurcations: computational studies with models reconstructed from magnetic resonance imaging of normal subjects.
PURPOSE The precise role played by hemodynamics, particularly wall shear stress, in the development and progression of vascular disease remains unclear, in large part because of a lack of in vivo studies with humans. Although technical challenges remain for noninvasively imaging wall shear stresses in humans, vascular anatomy can be imaged with sufficiently high resolution to allow reconstructi...
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